Article

A CDK-mediated phosphorylation switch of disordered protein condensation

2022-02-24

Abstract excerpt

<title>Abstract</title> <p>Cell cycle transitions arise from collective changes in protein phosphorylation states triggered by cyclin-dependent kinases (CDKs), but conceptual and mechanistic explanations for the abrupt cellular reorganisation that occurs upon mitotic entry are lacking. Specific interactions between distinct CDK-cyclin complexes and sequence motifs encoded in substrates might result in highly orde...

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Literature Corpus work: 62a48297-8e87-5e7a-8e01-80608039a129
DOI: 10.21203/rs.3.rs-1370895/v1

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