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Article

Targeted mutagenesis in chicken using CRISPR/Cas9 system.

Scientific reports - 6 Apr 2016

Oishi Isao, Yoshii Kyoko, Miyahara Daichi, Kagami Hiroshi, Tagami Takahiro

Abstract excerpt

The CRISPR/Cas9 system is a simple and powerful tool for genome editing in various organisms including livestock animals. However, the system has not been applied to poultry because of the difficulty in accessing their zygotes. Here we report the implementation of CRISPR/Cas9-mediated gene targeting in chickens. Two egg white genes, ovalbumin and ovomucoid, were efficiently (>90%) mutagenized in cultured chicken...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27050479
DOI: 10.1038/srep23980
PMCID: PMC4822141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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