Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome.

doi:10.1016/j.jneuroim.2016.02.001

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Article

Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome.

Journal of neuroimmunology - 15 Apr 2016

Yan J, Jm Greer, Pa McCombe

Abstract excerpt

Our study investigated the frequency of interleukin-6 (IL-6) promoter polymorphism rs1800795 (-174 G>C), possible association of this polymorphism with IL-6 levels and the outcome after stroke in 95 patients with acute ischemic stroke and 268 healthy subjects. It shows a significant reduction in the frequency of G alleles in stroke patients compared to healthy controls. Carriage of G allele is not associated with...

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PMID: 27049557
DOI: 10.1016/j.jneuroim.2016.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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