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Article

Interleukin-6 174G/C polymorphism and ischemic stroke: a systematic review.

Stroke - 1 Nov 2007

Tso Amy R, Merino José G, Warach Steven

Abstract excerpt

BACKGROUND AND PURPOSE: Interleukin-6 (IL-6) is associated with atherosclerotic disease and is also a key mediator in the inflammatory response to cerebral ischemia. Although the IL-6 -174G/C promoter polymorphism has been associated with carotid artery atherosclerosis and coronary heart disease, its relation to ischemic stroke is unclear. This review summarizes the current literature and discusses methodological...

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Source

Identifiers

PMID: 17916761
DOI: 10.1161/STROKEAHA.107.492231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interleukin-6 174G/C polymorphism and ischemic stroke: a systematic review.PMID 17916761Read ↗

Association between the interleukin-6-174 G/C polymorphism and risk of ischemic stroke: a meta-analysis.Semantic proximity Read ↗

Association between Interleukin-6 (G174C and G572C) promoter gene polymorphisms and risk of ischaemic stroke: A meta-analysisSemantic proximity Read ↗

A -174G/C polymorphism of the interleukin-6 gene in patients with lacunar infarction.Semantic proximity Read ↗

Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome.Semantic proximity Read ↗

Letter to the Editor "Association between the interleukin-6-174 G/C polymorphism and risk of ischemic stroke: a meta-analysis", published in Genet. Mol. Res. 14 (4): 13076-13083 (2015).Semantic proximity Read ↗

Association between interleukin-6 (G174C and C572G) promoter gene polymorphisms and risk of ischemic stroke in North Indian population: a case-control study.Semantic proximity Read ↗

Interleukin-6 gene -174 G/C promoter polymorphism predicts severity and outcome in acute ischemic stroke patients from north India.Semantic proximity Read ↗

The -174G/C polymorphism of the interleukin 6 gene is a hallmark of lacunar stroke and not other ischemic stroke phenotypes.Semantic proximity Read ↗

Lack of an association between interleukin-6 gene promoter polymorphisms (-174G/C, -572G/C) and ischemic heart disease and/or ischemic stroke: a meta-analysis.Semantic proximity Read ↗

Association of IL-6-174G > C and -572C > G polymorphisms with risk of young ischemic stroke patients.Semantic proximity Read ↗

The (-174) G/C polymorphism in the interleukin-6 gene is associated with the severity of acute cerebrovascular events.Semantic proximity Read ↗

PPARγ and IL-6 - 174G>C gene variants in Croatian patients with ischemic stroke.Semantic proximity Read ↗

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