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Lack of an association between interleukin-6 gene promoter polymorphisms (-174G/C, -572G/C) and ischemic heart disease and/or ischemic stroke: a meta-analysis.

Human immunology - 1 Aug 2011

Ma Ying, Tang Ren-Kuan, Yang Xu, Peng Guo-Guang, Liu Yun, Wang Xiao-Ming, Wu Bi-Hua, Yu Ju-Ming

Abstract excerpt

The association between single-nucleotide polymorphisms -174G/C (rs1800795) and -572G/C (rs1800796) in the interleukin-6 (IL-6) gene promoter region and ischemic heart disease (IHD)/ischemic stroke (IS) remains controversial and ambiguous. In this study, we performed a more precise estimation of the relationship by a meta-analysis based on currently available evidence from literature. To assess the effect of IL-6...

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PMID: 21536090
DOI: 10.1016/j.humimm.2011.03.019

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