Article
TNF-alpha -308G/A and IL-6 -174 G/C polymorphisms in the Turkish pediatric stroke patients.
Thrombosis research - 1 Jan 2005
Karahan Zeynep Ceren, Deda Gülhis, Sipahi Tansu, Elhan Atilla H, Akar Nejat
Abstract excerpt
INTRODUCTION: Introduction: Stroke is an important cause of mortality and morbidity in the pediatric age group. There is increasing evidence on the role of proinflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in the occurrence and outcome of stroke. These proinflammatory cytokines carry functional polymorphisms (IL-6 -174 G/C and TNF-alpha -308 G/A) in their promoter...
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