Article
The IL-6 G-174C polymorphism may be associated with ischaemic stroke in patients without a history of hypertension.
Irish journal of medical science - 1 Jan 2000
Balding J, Livingstone W J, Pittock S J, Mynett-Johnson L, Ahern T, Hodgson A, Smith O P
Abstract excerpt
BACKGROUND: Recent data suggest that inflammatory reactions are involved in the pathogenesis of cerebral ischaemia. AIM: To investigate whether certain inflammatory genetic polymorphisms are associated with the occurrence of ischaemic stroke. METHODS: We investigated the prevalence of six polymorphisms in cytokine genes (IL-6, TNF-alpha, TNF-beta, IL-1beta, IL-10, and IL-1Ralpha) in a group of ischaemic stroke...
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