Article
Interleukin-6 gene -174 G/C promoter polymorphism predicts severity and outcome in acute ischemic stroke patients from north India.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jul 2013
Chakraborty Baidarbhi, Chowdhury Debashish, Vishnoi Gaurav, Goswami Binita, Kishore Jugal, Agarwal Sarita
Abstract excerpt
BACKGROUND: A guanine/cytosine (G/C) substitution occurring in position -174 of the interleukin-6 (IL-6) gene promoter changes the expression of IL-6 circulating proteins. We evaluated the occurrence of IL-6 -174 G/C polymorphism in patients with acute ischemic stroke and studied its association with stroke severity, outcome, and mortality. METHODS: One hundred patients with acute ischemic stroke and 120 age and...
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