Article
Association between interleukin-6 (G174C and C572G) promoter gene polymorphisms and risk of ischemic stroke in North Indian population: a case-control study.
Neurological research - 1 Jan 2016
Kumar Pradeep, Kumar Amit, Sagar Ram, Misra Shubham, Faruq Mohammad, Suroliya Varun, Vivekanandhan Subiah, Kumar Srivastava Achal, Prasad Kameshwar
Abstract excerpt
BACKGROUND: Polymorphisms of G174C and C572G in the interleukin-6 (IL-6) promoter gene can affect both transcription and secretion of IL-6 and may be involved in inflammation related to and pathogenesis of ischemic stroke (IS). Whether these IL-6 gene polymorphisms are risk factors for IS or not, remains controversial. OBJECTIVE: The aim of this study was to determine the association between IL-6 G174C and C572G...
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