Article
Association of Interleukin-2, but not Interferon-Gamma, single nucleotide polymorphisms with juvenile idiopathic arthritis.
Allergologia et immunopathologia - 1 Jan 2000
Maddah M, Harsini S, Rezaei A, Sadr M, Zoghi S, Moradinejad M H, Ziaee V, Rezaei N
Abstract excerpt
BACKGROUND: Cytokines, including interleukin-2 (IL-2) and interferon-gamma (IFN-γ), seem to play a role in the pathogenesis of juvenile idiopathic arthritis (JIA). The aim of this study was to investigate the associations of IL-2 and IFN-γ single nucleotide polymorphisms (SNPs) with susceptibility to JIA in an Iranian population. METHODS: Genomic DNA of 54 Iranian patients with JIA and 139 healthy unrelated...
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