Article
Associations between interleukin-10 polymorphisms and susceptibility to juvenile idiopathic arthritis: a systematic review and meta-analysis.
European cytokine network - 1 Mar 2018
Harsini Sara, Saghazadeh Amene, Nedjat Saharnaz, Rezaei Nima
Abstract excerpt
BACKGROUND: Cytokine genes, including interleukin-10 (IL-10), are known to play important roles in the pathogenesis of juvenile idiopathic arthritis (JIA). This study aims to determine whether the IL-10 polymorphisms confer susceptibility to JIA. METHODS: A meta-analysis was performed on the associations between the IL-10 -1082 G/A, -592 C/A, and -819 C/T polymorphisms and JIA. A total number of 7 studies...
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