Article
Association of IL-10 gene polymorphisms and susceptibility to Juvenile Idiopathic Arthritis in Egyptian children and adolescents: a case-control study.
Italian journal of pediatrics - 17 Jan 2017
Fathy Manar M, Elsaadany Hosam F, Ali Yasser F, Farghaly Mohsen A A, Hamed Mohammed E, Ibrahim Hany E, Noah Maha A, Allah Mayy A N, Elashkar Shaimaa S A, Abdelsalam Nasser I, Abdelrahman Hind M, Ahmed Ahmed R, Anany Heba G, Ismail Sanaa M, Ibrahim Boshra R, Al Azizi Nashwa M, Gawish Heba H, Al-Akad Ghada M, Nabil Rehab M, Fahmy Dalia S, Alsayed Salah F
Abstract excerpt
BACKGROUND: Juvenile Idiopathic Arthritis (JIA) is the most common chronic arthritis in children worldwide. Among anti-inflammatory cytokines, interleukin-10 (IL-10) is a key immunosuppressive cytokine involved in the pathogenesis of JIA. To date, only a few studies concerned the association of interleukin-10 gene polymorphisms with JIA. In this study, we aimed to investigate 3 cytokine single-nucleotide...
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