Article
Association of tumour necrosis factor-alpha G/A -238 and G/A -308 single nucleotide polymorphisms with juvenile idiopathic arthritis.
International journal of immunogenetics - 1 Dec 2016
Maddah M, Harsini S, Ziaee V, Moradinejad M H, Rezaei A, Zoghi S, Sadr M, Aghighi Y, Rezaei N
Abstract excerpt
Juvenile idiopathic arthritis (JIA) is a heterogeneous autoimmune disorder of unknown origin. As proinflammatory cytokines are known to contribute towards the pathogenesis of JIA, this case-control study was performed to examine the associations of certain single nucleotide polymorphisms (SNPs) of tumour necrosis factor-α (TNF-α) gene. Fifty-three patients with JIA participated in this study as patients group and...
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