Article
Association of interleukin-1 family gene polymorphisms with juvenile idiopathic arthritis in Iranian population.
Allergologia et immunopathologia - 1 Jan 2000
Ziaee V, Maddah M, Harsini S, Rezaei A, Sadr M, Zoghi S, Moradinejad M H, Rezaei N
Abstract excerpt
BACKGROUND: Cytokines, including interleukin-1 (IL-1), seem to contribute towards the pathogenesis of juvenile idiopathic arthritis (JIA), so this study was designed to evaluate the associations of IL-1 gene cluster and IL-1 receptor (IL-1R) gene single nucleotide polymorphisms (SNPs) with JIA proneness in Iranian population. MATERIALS AND METHODS: Genomic DNA of 55 Iranian patients with JIA and 140 controls were...
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