Article
Association of interleukin-2 and interferon-γ single nucleotide polymorphisms with Juvenile systemic lupus erythematosus.
Allergologia et immunopathologia - 1 Jan 2000
Harsini S, Ziaee V, Tahghighi F, Mahmoudi M, Rezaei A, Soltani S, Sadr M, Moradinejad M H, Aghighi Y, Rezaei N
Abstract excerpt
PURPOSE: Juvenile systemic lupus erythematosus (JSLE) is a severe and chronic autoimmune disease of unknown origin. Inflammatory cytokines can play a pivotal role in the pathogenesis of JSLE, while their secretion is under genetic control. The current investigation was performed to analyse the associations of particular single nucleotide polymorphisms (SNPs) of interleukin-2 (IL-2) and interferon-gamma (IFN-γ)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
