Article
Autoimmune hepatitis association with single nucleotide polymorphism of interleukin-2, but not interferon-gamma.
Clinics and research in hepatology and gastroenterology - 1 Apr 2018
Yousefi Azizollah, Mahmoudi Elham, Baradaran Noveiry Behnoud, Zare Bidoki Alireza, Sadr Maryam, Motamed Farzaneh, Najafi Mehri, Farahmand Fatemeh, Khodadad Ahmad, Fallahi Gholam Hossein, Rezaei Nima
Abstract excerpt
BACKGROUND: Autoimmune hepatitis (AIH) is a chronic inflammation in hepatocellular tissues associated with circulating autoantibodies. Imbalance in T-cells population and dysregulation in several cytokine profiles has been implicated in pathogenesis of AIH. This study was performed to assess potential association of AIH with interleukin-2 (IL-2) and interferon-gamma (IFN-γ) genes single nucleotide polymorphisms...
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