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Article

Association of interleukin-6 single nucleotide polymorphisms with juvenile idiopathic arthritis.

Clinical rheumatology - 1 Jan 2017

Ziaee Vahid, Maddah Marzieh, Moradinejad Mohammad-Hassan, Rezaei Arezou, Zoghi Samaneh, Sadr Maryam, Harsini Sara, Rezaei Nima

Abstract excerpt

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children. Genetics and inflammatory elements seem to act as major underlying factors in its pathogenesis. The aim of this study is to identify the associations between interleukin-6 (IL-6) gene polymorphisms and individuals' vulnerability to JIA in a group of Iranian pediatric patients. Fifty-four patients with JIA were enrolled...

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PMID: 27646136
DOI: 10.1007/s10067-016-3407-6

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