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Article

Thermostabilization of the Human Endothelin Type B Receptor.

Journal of molecular biology - 5 Jun 2016

Okuta Akiko, Tani Kazutoshi, Nishimura Shoko, Fujiyoshi Yoshinori, Doi Tomoko

Abstract excerpt

The peptide hormone endothelin, produced by the vascular endothelium, is involved in several physiological functions, including maintenance of vascular tone and humoral homeostasis. Endothelin transmits signals through the endothelin receptor, a G-protein-coupled receptor. Structural studies of the endothelin type B receptor (ETBR) have been unsuccessful due to its structural flexibility and instability in...

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Identifiers

PMID: 27038509
DOI: 10.1016/j.jmb.2016.03.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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