Article

Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery

2019-12-28

Abstract excerpt

<h4>ABSTRACT</h4> Astrocytes play a number of key functions in health and disease. Reactivation of astrocytes occurs in most, if not all, neurological diseases. Most current information on the mechanisms underlying astrogliosis derives from studies using rodent experimental systems, mainly because the ability to study human astrocytes under healthy and pathological conditions has been hampered by the difficulty i...

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Literature Corpus work: 093f520a-ded6-5b7c-a0e3-a7944e4bb314
DOI: 10.1101/2019.12.28.890012

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