Article
Relationship between single nucleotide polymorphism of interleukin-18 and susceptibility to pulmonary tuberculosis in the Chinese Han population.
Microbiology and immunology - 1 Jun 2011
Han Min, Yue Jun, Lian Yuan-Yuan, Zhao Yan-Lin, Wang Hong-Xiu, Liu Li-Rong
Abstract excerpt
Interleukin-18 (IL-18) is a multi-functional cytokine capable of inducing either Th1 or Th2 polarization depending on the immunologic milieu. IL-18 may influence the host response to Mycobacterium tuberculosis (M.tb) infection. To investigate the relationship between single nucleotide polymorphisms of the IL-18 and susceptibility to pulmonary tuberculosis in the Chinese Han population, the IL-18 gene was...
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