Article
Influence of genetic polymorphisms of multidrug and toxin extrusion protein 1 on its mRNA expression in peripheral blood cells.
Journal of pharmacological sciences - 1 Jun 2016
Ando Hitoshi, Nakano Kazuhiko, Ushijima Kentaro, Kurokawa Shinsuke, Washino Satoshi, Hosohata Keiko, Morita Tatsuo, Fujimura Akio
Abstract excerpt
This study aimed to determine the effect of multidrug and toxin extrusion protein 1 (MATE1) genetic variants on its transcript expression in peripheral blood cells. Consistent with previous in vitro findings, MATE1 mRNA levels were significantly higher in subjects carrying rs2453579, but not rs2252281, compared to those without either of these promoter variants. In addition, the mRNA levels did not differ between...
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