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Article

Identification of amino acid variation in the prion protein associated with classical scrapie in Canadian dairy goats.

BMC veterinary research - 22 Mar 2016

Srithayakumar Vythegi, Mitchell Gordon B, White Bradley N

Abstract excerpt

BACKGROUND: A clear association of amino acid variation in the prion protein gene (PRNP) with susceptibility and resistance to classical scrapie exists in sheep, but not in goats. In this study we examined DNA sequence variation in the PRNP of 149 animals from two scrapie-infected herds of Saanen dairy goats, and identified 6 non-synonymous variants in the coding region. RESULTS: In the larger herd, all of the 54...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27005313
DOI: 10.1186/s12917-016-0684-x
PMCID: PMC4804529

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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