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Article

Identification of a new leucine haplotype (ALQ) at codon 154 in the ovine prion protein gene in Spanish sheep.

Journal of animal science - 1 Feb 2006

Alvarez L, Arranz J J, San Primitivo F

Abstract excerpt

Genetic susceptibility to scrapie is closely linked to variations at codons 136, 154, and 171 of the prion protein (PRNP) gene. This association between the PRNP genotype and susceptibility to scrapie is the basis of breeding programs for scrapie resistance in different countries. In this paper, we describe the method used with 2 Spanish dairy sheep breeds (Churra and Castellana) to ascertain the initial status...

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Source

Identifiers

PMID: 16424251
DOI: 10.2527/2006.842259x

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of a new leucine haplotype (ALQ) at codon 154 in the ovine prion protein gene in Spanish sheep.PMID 16424251Read ↗

Prion protein gene polymorphisms in healthy and scrapie-affected Spanish sheep.Semantic proximity Read ↗

Prion protein genotypes of Italian sheep breeds with lysine-171 and phenylalanine-141 detection.Semantic proximity Read ↗

Exploring the genetic variability of the PRNP gene at codons 127, 142, 146, 154, 211, 222, and 240 in goats farmed in the Lombardy Region, Italy.Semantic proximity Read ↗

PRNP haplotype and genotype frequencies in Brazilian sheep: issues for conservation and breeding programs.Semantic proximity Read ↗

Development of a real-time polymerase chain reaction assay for single nucleotide polymorphism genotyping codons 136, 154, and 171 of the prnp gene and application to Brazilian sheep herds.Semantic proximity Read ↗

PrP genotyping of Austrian sheep breeds.Semantic proximity Read ↗

Adaptation of a low-cost medium-throughput genotyping system for ovine prion protein gene polymorphims associated with scrapie.Semantic proximity Read ↗

PrP genotype frequencies and risk evaluation for scrapie in dairy sheep breeds from southern Italy.Semantic proximity Read ↗

Genetic profile of scrapie codons 146, 211 and 222 in the PRNP gene locus in three breeds of dairy goats.Semantic proximity Read ↗

Identification of amino acid variation in the prion protein associated with classical scrapie in Canadian dairy goats.Semantic proximity Read ↗

Identification of seven haplotypes of the caprine PrP gene at codons 127, 142, 154, 211, 222 and 240 in French Alpine and Saanen breeds and their association with classical scrapie.Semantic proximity Read ↗

Allelic variants of ovine prion protein gene (PRNP) in Oklahoma sheep.Semantic proximity Read ↗

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