Article
Polymorphism of the PRNP gene in the main breeds of indigenous Chinese goats.
Archives of virology - 1 Jan 2008
Zhou R Y, Li X L, Li L H, Wang H Y, Lü J G
Abstract excerpt
The polymorphism of the PRNP gene plays a key role in susceptibility to prion disease. Scrapie is a neurodegenerative disease affecting sheep and goats and belongs to the group of prion diseases. We isolated DNA from 333 goat samples representing the main local goat breeds in six provinces in China to identify PRNP polymorphisms and to determine whether these breeds were at risk for developing scrapie. Two novel...
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