Article
Prion gene (PRNP) haplotype variation in United States goat breeds (Open Access publication).
Genetics, selection, evolution : GSE - 1 Jan 2000
White Stephen, Herrmann-Hoesing Lynn, O'rourke Katherine, Waldron Daniel, Rowe Joan, Alverson Janet
Abstract excerpt
Scrapie eradication efforts cost 18 million dollars annually in the United States and rely heavily upon PRNP genotyping of sheep. Genetic resistance might reduce goat scrapie and limit the risk of goats serving as a scrapie reservoir, so PRNP coding sequences were examined from 446 goats of 10 breeds, 8 of which had not been previously examined at PRNP. The 10 observed alleles were all related to one of two...
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