Article
Prion protein gene polymorphisms in natural goat scrapie.
The Journal of general virology - 1 Mar 2002
Billinis Charalambos, Panagiotidis Cynthia H, Psychas Vassilios, Argyroudis Stamatis, Nicolaou Anna, Leontides Sotirios, Papadopoulos Orestis, Sklaviadis Theodoros
Abstract excerpt
A total of 51 goats, including seven clinical cases, from the first herd in Greece reported to have scrapie was examined to discern an association between scrapie susceptibility and polymorphisms of the gene encoding the prion protein (PrP). Each animal was evaluated for clinical signs of the disease, histopathological lesions associated with scrapie, the presence of detectable protease-resistant PrP in the brain...
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