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Article

Caprine PRNP polymorphisms at codons 171, 211, 222 and 240 in a Greek herd and their association with classical scrapie.

The Journal of general virology - 1 Jun 2010

Bouzalas Ilias G, Dovas Chrysostomos I, Banos Georgios, Papanastasopoulou Maria, Kritas Spyridon, Oevermann Anna, Papakostaki Dimitra, Evangelia Chatzinasiou, Papadopoulos Orestis, Seuberlich Torsten, Koptopoulos Georgios

Abstract excerpt

The association between PRNP variation and scrapie incidence was investigated in a highly affected Greek goat herd. Four mutations were identified at codons 171Q/R, 211R/Q, 222Q/K and 240P/S. Lysine at codon 222 was found to be associated with the protection from natural scrapie (P=0.0111). Gluta...

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Source

Identifiers

PMID: 20107013
DOI: 10.1099/vir.0.017350-0

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20107013-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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