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Article

Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase.

Biochemistry - 12 Apr 2016

Raper Austin T, Gadkari Varun V, Maxwell Brian A, Suo Zucai

Abstract excerpt

Y-family DNA polymerases are known to bypass DNA lesions in vitro and in vivo and rescue stalled DNA replication machinery. Dpo4, a well-characterized model Y-family DNA polymerase, is known to catalyze translesion synthesis across a variety of DNA lesions including 8-oxo-7,8-dihydro-2'-deoxyguanine (8-oxo-dG). Our previous X-ray crystallographic, stopped-flow Förster resonance energy transfer (FRET), and...

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Identifiers

PMID: 27002236
DOI: 10.1021/acs.biochem.6b00166
PMCID: PMC5026495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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