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Article

Mechanism of abasic lesion bypass catalyzed by a Y-family DNA polymerase.

The Journal of biological chemistry - 16 Mar 2007

Fiala Kevin A, Hypes Cameron D, Suo Zucai

Abstract excerpt

The 3 million-base pair genome of Sulfolobus solfataricus likely undergoes depurination/depyrimidination frequently in vivo. These unrepaired abasic lesions are expected to be bypassed by Dpo4, the only Y-family DNA polymerase from S. solfataricus. Interestingly, these error-prone Y-family enzyme...

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Identifiers

PMID: 17210571
DOI: 10.1074/jbc.M610718200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17210571-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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