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Article

Analysis of polymorphisms of genes associated with folate-mediated one-carbon metabolism and neural tube defects in Chinese Han Population.

Birth defects research. Part A, Clinical and molecular teratology - 1 Apr 2016

Piao Wei, Guo Jin, Bao Yihua, Wang Fang, Zhang Ting, Huo Junsheng, Zhang Kunlin

Abstract excerpt

BACKGROUND: The polymorphism of genes involved in folate-mediated one-carbon metabolism may be a risk factor for neural tube defects (NTDs). In the present study, we aimed to investigate the single nucleotide polymorphisms (SNPs) of the genes BHMT, CUBN, FTCD, GAMT, GART, SARDH, SHMT1, and MUT, and their effect on NTDs in the Chinese Han population. METHODS: A total of 270 NTDs cases and 192 controls were...

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Source

Identifiers

PMID: 27001897
DOI: 10.1002/bdra.23478

Genes

SARDH
BHMT
CUBN
FTCD
GAMT
GART
SHMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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