Article
Study on the relationship between genetic polymorphism of reductive folic acid carrier and the risk of neural tube defects.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Jul 2023
Yang Xusen, Fan Guofeng, Wang Zengliang, Li Shaoshan, Qin Hu, Wang Yun, Ma Xiaohu, Ji Wenyu, Wang Yongxin
Abstract excerpt
BACKGROUND: To investigate the association of folate metabolism gene polymorphism with neural tube defects (NTDs) in Chinese population. METHODS: The subjects were divided into two groups, 495 children with NTDs (NTD group) and 255 healthy children (control group). RESULTS: The levels of folic acid, s-adenosine methionine (SAM), and Sam/s-adenosine homocysteine (SAH) in NTD group were lower than those in control...
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