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Article

Association of neural tube defects with gene polymorphisms in one-carbon metabolic pathway.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Feb 2018

Cao Lirong, Wang Yizheng, Zhang Ruiping, Dong Liang, Cui Hualei, Fang Yulian, Zhao Linsheng, Shi Ouyan, Cai Chunquan

Abstract excerpt

PURPOSE: Neural tube defects (NTDs) are common congenital malformations. In this study, we aimed to explore the association between single nucleotide polymorphisms (SNPs) related to one-carbon metabolism (OCM) and NTDs in Han population of Northern China. METHODS: A case-control study was conducted in 152 children with NTDs and 169 controls. Twenty-nine SNPs in five genes were genotyped by Sequenom MassARRAY...

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Source

Identifiers

PMID: 28770393
DOI: 10.1007/s00381-017-3558-z

Genes

BHMT
MTR
RFC1
OCM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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