Article
Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/β-catenin signaling pathway mutations.
Cancer - 1 Jun 2016
Yuan Wei, Zhang Zhou, Dai Binghua, Wei Qing, Liu Jinjin, Liu Yuzhen, Liu Yun, He Lin, Zhou Daizhan
Abstract excerpt
BACKGROUND: Genomic alterations of small bowel cancers remain poorly understood due to the rarity of these diseases. In the current study, the authors report the identification of somatic mutations from patients with duodenal adenocarcinoma by whole-exome sequencing. METHODS: Whole-exome sequencing and follow-up analysis were conducted in 12 matched tumor-normal tissue duodenal adenocarcinoma tissue pairs to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.