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Article

Molecular Advances in Gastrointestinal Pathology.

Seminars in diagnostic pathology - 1 Mar 2026

Das Avash, Chetta Paolo M, Zhang M Lisa

Abstract excerpt

Gastrointestinal adenocarcinomas, including colorectal cancer (CRC) and gastroesophageal junction (GEJ) carcinoma, represent a significant global health burden. Recent advances in large-scale multi-omics profiling, particularly through The Cancer Genome Atlas (TCGA), have revealed the genetic heterogeneity and underlying biology of these tumors. Integrating molecular biomarkers with histopathology into routine...

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Source

Identifiers

PMID: 41633080
DOI: 10.1016/j.semdp.2026.150990

Genes

CLDN18
BRAF
KRAS
PIK3CA
POLE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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