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Article

Targeted sequencing-based analyses of candidate gene variants in ulcerative colitis-associated colorectal neoplasia.

British journal of cancer - 27 Jun 2017

Chakrabarty Sanjiban, Varghese Vinay Koshy, Sahu Pranoy, Jayaram Pradyumna, Shivakumar Bhadravathi M, Pai Cannanore Ganesh, Satyamoorthy Kapaettu

Abstract excerpt

BACKGROUND: Long-standing ulcerative colitis (UC) leading to colorectal cancer (CRC) is one of the most serious and life-threatening consequences acknowledged globally. Ulcerative colitis-associated colorectal carcinogenesis showed distinct molecular alterations when compared with sporadic colorectal carcinoma. METHODS: Targeted sequencing of 409 genes in tissue samples of 18 long-standing UC subjects at high...

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Share to Activin Receptors, Type II
Share to Adenomatous Polyposis Coli Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colitis, Ulcerative

Share to Dioxygenases

Share to Histone-Lysine N-Methyltransferase

Share to Proto-Oncogene Proteins c-raf

Share to Receptor, Fibroblast Growth Factor, Type 2

Share to Receptor, Fibroblast Growth Factor, Type 3

Source

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Identifiers

PMID: 28524162
DOI: 10.1038/bjc.2017.148
PMCID: PMC5520210

Genes

APC
FGFR2
FGFR3
KRAS
MTOR
RAF1
SETD2
SMARCA4
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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