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Article

Genomic Profiling of Small-Bowel Adenocarcinoma.

JAMA oncology - 1 Nov 2017

Schrock Alexa B, Devoe Craig E, McWilliams Robert, Sun James, Aparicio Thomas, Stephens Philip J, Ross Jeffrey S, Wilson Richard, Miller Vincent A, Ali Siraj M, Overman Michael J

Abstract excerpt

IMPORTANCE: Small-bowel adenocarcinomas (SBAs) are rare cancers with a significantly lower incidence, later stage at diagnosis, and worse overall survival than other intestinal-derived cancers. To date, comprehensive genomic analysis of SBA is lacking. OBJECTIVE: To perform in-depth genomic characterization of a large series of SBAs and other gastrointestinal tumors to draw comparisons and identify potentially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28617917
DOI: 10.1001/jamaoncol.2017.1051
PMCID: PMC5710195

Genes

APC
BRAF
ERBB2
KRAS
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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