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Article

The Balancing Act of Ribonucleotides in DNA.

Trends in biochemical sciences - 1 May 2016

Cerritelli Susana M, Crouch Robert J

Abstract excerpt

The abundance of ribonucleotides in DNA remained undetected until recently because they are efficiently removed by the ribonucleotide excision repair (RER) pathway, a process similar to Okazaki fragment (OF) processing after incision by Ribonuclease H2 (RNase H2). All DNA polymerases incorporate ribonucleotides during DNA synthesis. How many, when, and why they are incorporated has been the focus of intense work...

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Identifiers

PMID: 26996833
DOI: 10.1016/j.tibs.2016.02.005
PMCID: PMC4851601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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