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Article

Dynamic changes of driver genes' mutations across clinical stages in nine cancer types.

Cancer medicine - 1 Jul 2016

Li Xia

Abstract excerpt

The driver genes play critical roles for tumorigenesis, and the number of identified driver genes reached plateau. But how they act during different cancer development stages is lack of knowledge. We investigated 138 driver genes' mutation changes across clinical stages using 3,477 cases in nine cancer types from the Cancer Genome Atlas (TCGA) and constructed their temporal order relationships. We also examined...

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Identifiers

PMID: 26992457
DOI: 10.1002/cam4.704
PMCID: PMC4944883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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