Article
Mutational Landscape of Cancer-Driver Genes Across Human Cancers
2022-09-11
Abstract excerpt
The cancer driver genes are involved in transforming healthy cells into cancerous cells. The molecular aberrations which lead to cancer involve gain and loss of function mutations in various cancer driver genes. Here, we examine the genome sequences of 20,066 primary tumours representing 43 distinct human cancers to identify and catalogue driver mutations in 729 known cancer genes. We show that the frequency of dr...
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Identifiers and source
- Literature Corpus work
- c4319061-7557-5cc3-8afc-b8feed55f599
- DOI
- 10.1101/2022.09.11.507448