Article
Evolutionary mechanism unifies the hallmarks of cancer.
International journal of cancer - 1 May 2015
Horne Steven D, Pollick Sarah A, Heng Henry H Q
Abstract excerpt
The basis for the gene mutation theory of cancer that dominates current molecular cancer research consists of: the belief that gene-level aberrations such as mutations are the main cause of cancers, the concept that stepwise gene mutation accumulation drives cancer progression, and the hallmarks of cancer. The research community swiftly embraced the hallmarks of cancer, as such synthesis has supported the notions...
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