Article
Somatic gene mutation signatures predict cancer type and prognosis in multiple cancers with pan-cancer 1000 gene panel.
Cancer letters - 1 Feb 2020
Wang Hai-Long, Liu Peng-Fei, Yue Jie, Jiang Wen-Hua, Cui Yun-Long, Ren He, Wang Han, Zhuang Yan, Liu Yong, Jiang Da, Dong Qian, Zhang Hui, Mi Jia-Hui, Xu Zan-Mei, Tian Cai-Juan, Zhang Zhen-Zhen, Wang Xiao-Wei, Su Mei-Na, Lu Wei
Abstract excerpt
Most cancers are caused by somatic mutations. Some common mutations in the same cancer type can form a "signature" to specifically predict the prognosis or to distinguish it from other cancers. In this study, 710 somatic cell mutations were identified in 142 cases, including digestive, lung and urogenital cancers, and the digestive cancers were further divided into liver, stomach, intestinal, esophageal and...
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