Article
Functional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitis.
Proceedings of the National Academy of Sciences of the United States of America - 29 Mar 2016
Savva Athina, Brouwer Matthijs C, Roger Thierry, Valls Serón Mercedes, Le Roy Didier, Ferwerda Bart, van der Ende Arie, Bochud Pierre-Yves, van de Beek Diederik, Calandra Thierry
Abstract excerpt
Pneumococcal meningitis is the most frequent and critical type of bacterial meningitis. Because cytokines play an important role in the pathogenesis of bacterial meningitis, we examined whether functional polymorphisms of the proinflammatory cytokine macrophage migration inhibitory factor (MIF) were associated with morbidity and mortality of pneumococcal meningitis. Two functional MIF promoter polymorphisms, a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.