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Article

Association of macrophage migration inhibitory factor (MIF) polymorphisms with risk of meningitis from Streptococcus pneumoniae.

Cytokine - 1 Mar 2011

Doernberg Sarah, Schaaf Bernhard, Dalhoff Klaus, Leng Lin, Beitin Anna, Quagliarello Vincent, Bucala Richard

Abstract excerpt

Macrophage migration inhibitory factor (MIF) is an upstream proinflammatory cytokine encoded by a functionally polymorphic locus. This study of 119 patients explored the potential relationship between MIF genotype and invasive Streptococcus pneumoniae infections. We observed an association between a high-expression MIF allele and occurrence of pneumococcal meningitis.

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Source

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Identifiers

PMID: 21208809
DOI: 10.1016/j.cyto.2010.12.010
PMCID: PMC3033983

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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