Article
Toll-like receptor 9 polymorphisms are associated with severity variables in a cohort of meningococcal meningitis survivors.
BMC infectious diseases - 11 May 2012
Sanders Marieke S, van Well Gijs T J, Ouburg Sander, Morré Servaas A, van Furth A Marceline
Abstract excerpt
BACKGROUND: Genetic variation in immune response genes is associated with susceptibility and severity of infectious diseases. Toll-like receptor (TLR) 9 polymorphisms are associated with susceptibility to develop meningococcal meningitis (MM). The aim of this study is to compare genotype distributions of two TLR9 polymorphisms between clinical severity variables in MM survivors. METHODS: We used DNA samples of a...
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