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Article

Macrophage migration inhibitory factor promotes clearance of pneumococcal colonization.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 2014

Das Rituparna, LaRose Meredith I, Hergott Christopher B, Leng Lin, Bucala Richard, Weiser Jeffrey N

Abstract excerpt

Human genetic polymorphisms associated with decreased expression of macrophage migration inhibitory factor (MIF) have been linked to the risk of community-acquired pneumonia. Because Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and nasal carriage is a precursor to invasive disease, we explored the role of MIF in the clearance of pneumococcal colonization in a mouse model....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24928996
DOI: 10.4049/jimmunol.1400133
PMCID: PMC4085577

Genes

MIF
CCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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