Article
How many single-nucleotide polymorphisms (SNPs) must be tested in order to prove susceptibility to bacterial meningitis in children? Analysis of 11 SNPs in seven genes involved in the immune response and their effect on the susceptibility to bacterial meningitis in children.
Innate immunity - 1 Apr 2018
Gowin Ewelina, Świątek-Kościelna Bogna, Kałużna Ewelina, Strauss Ewa, Wysocki Jacek, Nowak Jerzy, Michalak Michał, Januszkiewicz-Lewandowska Danuta
Abstract excerpt
The aim of this study is to describe the prevalence of single single-nucleotide polymorphisms (SNPs) as well as their combinations in genes encoding proteins involved in the immune response in children with bacterial meningitis. The prospective study group consisted of 39 children with bacterial meningitis and 49 family members surveyed between 2012 and 2016. Eleven SNPs in seven genes involved in immune response...
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