Functional polymorphisms in the gene encoding macrophage migration inhibitory factor (MIF) are associated with active pulmonary tuberculosis.

doi:10.3109/23744235.2015.1107188

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Article

Functional polymorphisms in the gene encoding macrophage migration inhibitory factor (MIF) are associated with active pulmonary tuberculosis.

Infectious diseases (London, England) - 1 Jan 2016

Kuai Shou-Gang, Ou Qin-Fang, You De-Hong, Shang Zhong-Bo, Wang Jun, Liu Jun, Zhou Xi-Ke, Pei Hao, Huang Li-Hua

Abstract excerpt

OBJECTIVE: The role of the cytokine, macrophage migration inhibition factor (MIF) was assessed in tuberculosis. This case-control study investigated whether commonly occurring functional MIF polymorphisms are associated with active tuberculosis as well as with serum levels of MIF, IFN-γ and TNF-α. METHODS: Two MIF promoter polymorphisms, a functional -794 CATT5-8 microsatellite repeat (rs5844572) and a -173G/C...

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PMID: 26542751
DOI: 10.3109/23744235.2015.1107188

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