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Article

The influence of macrophage migration inhibitory factor gene polymorphisms on outcome from community-acquired pneumonia.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2009

Yende Sachin, Angus Derek C, Kong Lan, Kellum John A, Weissfeld Lisa, Ferrell Robert, Finegold David, Carter Melinda, Leng Lin, Peng Zhi-Yong, Bucala Richard

Abstract excerpt

The cytokine, macrophage migration inhibitory factor (MIF), is encoded in a functionally polymorphic locus and subjects with high-expression MIF alleles are at an increased risk of inflammatory disease. Severe sepsis is the leading cause of death in intensive care units, and the prevailing hypothesis is that an excessive innate response contributes to its pathogenesis. To assess if MIF alleles influence the...

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Source

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Identifiers

PMID: 19346297
DOI: 10.1096/fj.09-129445
PMCID: PMC2717777

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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