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Article

Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy.

PloS one - 1 Jan 2016

Pai Chen-Hsueh, Yen Ching-Tzu, Chen Chie-Pein, Yu I-Shing, Lin Shu-Wha, Lin Shu-Rung

Abstract excerpt

Preeclampsia (PE) is a potentially fatal pregnancy-related hypertensive disorder characterized by poor placenta development that can cause fetal growth restriction. PE-associated pathologies, including thrombosis, hypertension, and impaired placental development, may result from imbalances between thromboxane A2 (TXA2) and prostacyclin. Low-dose aspirin, which selectively inhibits TXA2 production, is used to...

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Identifiers

PMID: 26974824
DOI: 10.1371/journal.pone.0151617
PMCID: PMC4790927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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