Article

High-salt diet disturbs the physiological uterine endothelial junction remodeling during pregnancy

2025-11-07

Abstract excerpt

A high-salt diet (HSD) induced excessive sodium intake is a major risk factor for various diseases. However, its specific effects on uterine endothelial cell and pregnancy outcomes remain poorly understood. In this study, we demonstrated that HSD induces gestation specific hypertension and adverse pregnancy outcomes in murine models. The proper spiral artery remodeling, which involved the decidual vascular endothe...

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Literature Corpus work: 59d09f8f-f873-59b2-9cdf-04d55e553d8d
DOI: 10.1101/2025.11.06.687038

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